The Indigo Plugin for Plex duplicates much of the functionality of Indigo's web and iPhone clients, making it possible to control your home automation system with a click of the remote. This plugin should work equally well when Plex and Indigo are on the same machine, on different machines on the same intranet, or across the internet.
Indigo for Plex requires:
Indigo 4.X or above, with the server running independently of the client application
Remote access allowed (with or without authentication)